Theme: What’s New, What’s Relevant to Nigeria?
Date: 1 – 5 September, 2014
The newly inaugurated Board of the Hospital Management has commenced its assignment with the pledge to lift up the standard of health care delivery services in the hospital.
The Board, under the Chiarmanship of Alhaji Sanusi Baban Takko (Barayan Bauchi) gave the assurance at the maiden meeting of the Board held in the hospital recently.
The Chairman solicited the support of the entire staff of the hospital in the onerous task of re-positioning and re-engineering the hospital for excellent medicare.
The new Board members are as follows:
Given the complexities of our nation’s economic and socio-political climates and the attendant dysfunctions and dislocation of many human endeavours, seeing any institution brazenly ride against the tidesto stardom calls for due recognition and attention.
This becomes even more compelling when such an institution belongs to a group classified as service-oriented and non-profit making.
The fore-going aptly describes the success story of the Federal Medical Centre, Idi-Aba, Abeokuta a 250-bedded regional specialist hospital which came into existence on 21st April 1993, thus turning Twenty in April this year .
Within its relatively ‘few’ years of existence, the hospital had carved a niche for itself as primus inter pares arising from its significant contributions to the fields of medicine, training and research.
At an International Conference that held recently in Abeokuta, the Ogun State Capital, the Hospital’s Medical Director, Dr Oladapo Sunday Sotiloye brilliantly brought the message home to his diverse audiences when he said the hospital within its twenty years of existence has continued to be “locally relevant and globally visible in theareas of excellent medical services, research and training”.
A trip down the memory lane indicated that the hospital was inaugurated in 1993 following the handover by the then state HospitalIdi-Aba by former Ogun State Governor Chief Olusegun Osoba to the Federal Government for development into a Federal Tertiary Health Hospital for the people of Ogun State and Nigerians in general.
This was in fulfillment of the National Health Policy that states that the “Federal Government of Nigeria was committed to the establishment of a tertiary health institution in every state that did not have a teaching hospital.
At inception, the hospital took off as a tertiary health institution with the philosophy of excellence in the provision of medical services to the people of Ogun State and the neighboring states and nations. However, over the recent years, the scope of this philosophy has gradually expanded to further encompass excellence in training and research, so that today we can rightly say that the hospital stands on a tripod of excellence in research, training and healthcare service delivery.
With very limited infrastructure and trained personnel at its infancy period, the hospital has witnessed a phenomenal transformation in infrastructure and manpower development over the last two decades.
As against three departments at inception, the hospital recently boasts of over 30 departments and over 50 specialists in the various fields of medicine. With less than 50 beds at the take off, the hospital presently has over 250 beds.
Federal Medical Centre, Abeokuta is an accredited Centre for residency training in the specialties of Obstetrics and Gynaecology, Internal Medicine, Family Medicine and Paediatrics while plans are at an advanced stage to commence training in Surgery, Anaesthesia and Radiology.
Internship training also takes place in Medicine, Pharmacy, Radiograph yPhysiotherapy and Medical Laboratory Sciences. Undergraduate medical and allied health sciences students from local and foreign medical schools have been undertaking clinical attachments in the hospital for periods of varying durations.
Nursing students from the state-owned school of Nursing also regularly undergo their practical nursing training on the wards of the hospital.
Besides, consultant staff of the hospital regularly undertake additional programmes within and outside the country as well as participate actively in local and international conferences.
Within its short period of existence, the hospital has impacted positively on the growth of medicine in the country and has earned some local and international recognition.
Speaking during a visit to the Hospital on the 26th February, 1998, the former Health Minister, Prof. Iyorwese Hugher said
The FMC here is really justifying the goals for which it was established. I am impressed with the very high level of maintenance culture and the calibre of staff.
Similarly, the former Minister of State for Health, Arc Halima Tayo Alao on a visit to the Hospital in 2006 had this to say
“I commend most sincerely the efforts of the Management and staff of this Centre.Please keep up the good work”.
The former Finance Minister, Dr. Onaolapo Soleye on a visit to the Centre remarked;
An exceptionally clean environment inspite of the dwindling resources. This is unscheduled visit, highly impressed with the environment and the commitment of the employees.We must assist to make this Centre great and greater.
Definitely, the journey of the hospital over the past 20 years has been frought with several challenges. Kudos must however be given to the visionary leadership in which the hospital was blessed with.
The Pioneer Medical Director, Professor Emmanuel Oladipo Otolorin in the beginning grappled with the myriad of daunting constraints to bring the hospital to a sound footing.
His successor Dr. Theophilus Olujimi Motayo did his best to sustain and improve upon the several innovations of his predecessor.
Impressively, due attention must be paid to the forthrightness, dedication, commitment and purposeful leadership of the current Medical Director,
Dr Oladapo Sunday Sotiloye who within a short time in office had consciously and conscientiously transformed the fortunes of the hospital.
More infrastructures were being provided, services were being expanded while staff training and re-training was accorded a high premium in the scheme of things in the hospital.
To mention just a few, the purposeful and result –oriented leadership of the Dr Sotiloye led administration has dynamically and methodically changed the landscape of the Hospital by undertaken the construction of new structures and provision of basic amenities which included the following:
Already, work is nearing completion on the construction of a Modular Theatre to comprise of 8 suites and a 4-wing complex to house ENT/ Ophthalmology and Physiotherapy Department, incorporating the GYM.
In order to address the seemingly intractable erratic electricity and water supplies to the Centrewhich were common phenomena since inception, the current leadership took the bull by the horns by successfullyconnecting the Centre to a 33KVA National grid. In addition a brand new 500KVA Generator set was procured through the Internally Generated Revenue to serve as a back up.
Considering the importance of water to the day-to-day running of the Centre, the Management resuscitated some of the abandoned bore holes, sank new ones and successfully re-connected the hospital to the major public mains.
Similarly, new internal roads were constructed to ease vehicular movement within the hospital complex while old ones were successfully rehabilitated.
All of these pragmatic initiatives have continued to yield positive results in the smooth discharge of health care delivery services in the Hospital.
Through wit and tact and uncanny wisdom, the staffare well motivated to discharge their professional obligations enthusiastically which has continued to result in the high number of hospital patronage.
The Medical Director, Dr Sotiloye has assured the teeming patients and clients of the hospital to continue to look forward to improved health care delivery services in the Centre in the years ahead.
At Twenty, the Federal Medical Centre, Idi-Aba Abeokuta is indeed a locally relevant and globally visible health institution.
Written By: Segun Orisajo, Public Relations Executive of Federal Medical Centre, Abeokuta.
The following are the approved list of candidates who were successful at the Senior Staff Appointment Interview conducted on the 6th December, 2012 at the Federal Medical Centre, Abeokuta
APPOINTMENT POST: ARCHITECT GRADE I
1 Muraino Hassan Olalekan
APPOINTMENT POST: BIOMEDICAL ENGR./BIOMEDICAL TECHNICIAN
1 Sam Nelson
2 Oderinde Taoreed O.
APPOINTMENT POST: CONSULTANT PATHOLOGIST (MEDICAL MICROBIOLOGIST)
1 Nwadike Victor Ugo chukwu
APPOINTMENT POST: CONSULTANT PATHOLOGIST (CHEMICAL PATHOLOGIST)
1 Olawale Olatunbosun Oladipupo
APPOINTMENT POST: CONSULTANT (INTENSIVIST)
1 Akpan Imeh james
APPOINTMENT POST: CONSULTANT DENTAL SURGEON (RESTORATIVE)
1 Abu Aliu
APPOINTMENT POST: CONSULTANT FAMILY MEDICINE
1 Ige Adegbola Meedeen
APPOINTMENT POST: CONSULTANT (GYNAECOLOGY ONCOLOGIST)
1 Ogunfunmilayo Taofeek Ajani
APPOINTMENT POST: CONSULTANT NEONATOLOGIST
1 Agbo Donatus Domnie
APPOINTMENT POST: CONSULTANT ORTHOPAEDIC SURGEON
1 Uzodimma Charles Cinnedu
2 Ganiyu Isiaka Affolabi
APPOINTMENT POST: CONSULTANT PAEDIATRIC CARDIOLOGIST
1 Uzodimna Chinyere Chikodili
APPOINTMENT POST: CONSULTANT PAEDIATRIC SURGEON
1 Adesanya Opeoluwa
APPOINTMENT POST: CONSULTANT (PLASTIC SURGEON)
1 Akindipe Jabez Ariyo
APPOINTMENT POST: CONSULTANT RADIOLOGIST
1 Ogunmoroti Olusanmi Abel
APPOINTMENT POST: CONSULTANT DERMATOLOGIST
1 Oke Olaide Olutoyin
APPOINTMENT POST: DENTAL TECHNOLOGIST GRADE II
1 Arinze Uramaka Anthonia
2 Fasugba Anu Alaba
APPOINTMENT POST: DENTAL THERAPIST
1 Awosusi Gabriel Richard
2 Ogunbowale Margret Opeyemi
APPOINTMENT POST: EEG TECHNICIAN
1 Akintola Oluyomi Adedoja
2 Abugu Kenneth C.
APPOINTMENT POST: HIGHER DIETICIAN OFFICER
1 Olubiyi Simisola Hannah
APPOINTMENT POST: REGISTRAR (PAEDIATRICS)
1 Alao Samsudeen Opeyemi
1 Evwibovwe Efe
2 Abayomi-Alli Titilayo Funmilayo
3 Akinseinde Joyce A.
4 Olatayo Martina Ilobekemhen
5 Owolabi Olasunkanmi
6 Ugbaja Virginia O.
7 Adeogun Oluwaseyi Babatunde
APPOINTMENT POST: HEALTH RECORDS OFFICER II
1 Otunta Ode Kenneth
2 Bakare, Monsurat Morisade
APPOINTMENT POST: HEALTH RECORDS TECHNICIAN
1 Ozoemena Leo Nwabueze
2 Sajowa Inioluwa Victoria
APPOINTMENT POST: MEDICAL IMAGING SCIENTIST (RADIOGRAPHER)
1 Joseph Gladys Afone
2 Oko Chritian Aleke
APPOINTMENT POST: MEDICAL LABORATORY SCIENTIST
1 Ezeani Maduabuchi Isreal
2 Oyewo Oluwatosin J.
3 Olatunji Omosefe Faith
APPOINTMENT POST: REGISTRAR (INTERNAL MEDICINE)
1 Dr. Oladeji Olajide Olumuyiwa
2 Uduagbamen Peter Kehinde
3 Okoli Ezeagozie Leo
4 Omololu Ayanfe Samuel
5 Jeminiwa Bamidele Oluwaseun
6 Njepuome Tochukwu Emmanuel
7 Dr. Oluwagbemi Yetunde
APPOINTMENT POST: REGISTRAR (FAMILY MEDICINE)
1 Dr. Ayilara Saheed Alao
2 Odebunmi Olufisayo Oyewe
3 Raji Adesola Akinbola
4 Erinoso Adekunle Ayotunde
5 Kareem Mutiu O.
6 Jimoh adekunle Olayinka
7 Adeyemo J. Adesoji
APPOINTMENT POST: DENTAL OFFICER
1 Dr. Oludiran Oladapo D.
2 Dr. Ibrahim Musefiu Oyedeji
3 Dr. Koledoye Omotunde Abiola
4 Dr. Adejuwon Chinenye Nwando
APPOINTMENT POST: MEDICAL OFFICER
1 Dr. Soyemi Adeola Mojisola
2 Dr. Ovwigho Edafegwotv Ohohi
3 Dr. Akinsanpe Adewale Adetayo
4 Dr. Yusuff Hammed Ayodeji
5 Dr. Elegberun Nancy Ojo
6 Dr. Onyekachi Uzodinma
7 Dr. Oyetunji S. A.
8 Dr. Ogunnaike Quaye T.B.
9 Dr. Rwang Pam Haruna
APPOINTMENT POST: REGISTRAR (OBS. & GYNAE.)
1 Dr. Adekeye Micheal Gbenga
2 Dr. Ade-Onajobi Adedoyin Olatunde
3 Dr. Osuji Nwabueze Gabriel
4 Dr. Adenaya Olaide Rufus
5 Dr. Abdussalam Hameedat Opeyemi
6 Dr. Chukmunyere Chibuke Friday
7 Dr. Okusanya O. Abimbola
8 Dr. Apelehin O. A.
APPOINTMENT POST: NURSING OFFICER II
1 Nnodim Nancy Chioma
2 Julius Chineye Sunday
3 Olaniyi Ebenezer Femi
4 Olabiyi Bimpe Abiodun
5 Adegbe Jane Kasuwa
6 Iriri Rosemary
7 Osunwoke Vivianmary sandra Udoka
8 Oluwadare Olubunmi Mary
APPOINTMENT POST: NURSING SUPERINTENDENT
1 Adeosun Adebisi Aderoju
2 Olojede Oluyemisi Temitope
3 Durowoju Fasilat Adetutu
4 Olatunji Dolapo Olawumi
5 Ayelotiti Modupeola Sekinat
6 Daniel Elizabeth
7 Ogundele Bunmi Elizabeth
8 Fejoh abosede Alice
9 Olanrewaju Tosin Mary
10 Ogoke Uche Assumpta
11 Kusimo damilola Omolola
12 Odejobi Omolola Oluwaseun
13 Ogundare Olufunke Bolaji
14 Oloyede Surajat Olaide
15 Balogun Omolara Abosede
16 Osho Rukayat Eniola
17 Ojebiyi Aderonke Olubunmi
18 Olusanya Olupelumi Oluseyi
19 Ogundimu Adebola Janet
20 Oyetade Oluwakemi Gloria
21 Nnabuihe Esther Nkechi
22 Oforkansi Stella Ebehiremen
23 Osinaike Yetunde Afolake
24 Oke Abisola Morounfolu
25 Olusanjo Oluwatosin
26 Koshoffa Margaret Folakemi
27 Olaoni Rhoda Olayinka
28 Okoye Mary Obiageli
29 Alalade Anuoluwapo Desola
30 Oyejide Abosede Abisoye
31 Olabode Abiola Abosede
32 Ayodeji Aminat Iyabode
33 Akerele Oluwapelumi Busayo
34 Odubawo Omolara Oluwakemi
35 Sunday Atinuke Seling
36 Sonaya Oluwaseun Jumoke
37 Olubori Ololade Morufat
38 Abiodun Aishat Olasunbo
39 Salako Olajumoke Aminat
40 Olaniran Olaronke Olajoke
41 Sanusi Rahmat Modupe
42 Omosigho Jummai Bature
43 Durowoju Biola Sadiat
44 Akinlade Shukurat Olayemi
45 Taire Eben
46 Eludiwura Aderemi Veronica
47 Lasisi Kamilat akorede
48 Ugwu Nnedinma Chizoba
49 Ajibola Ayobami Oluwakemi
50 Adenuga Bukola Abigail
51 Erinoso Christianah Remi
52 Erinoso Kafayat Omorilewa
53 Olorode Bilikisu Odunayo
54 Ojo Olusola Josephine
55 Adefemi Victoria Toyin
56 Adebayo Mary Ireoluwa
57 Olawale Nosirat Adebimpe
58 Tomisin-Olu Temitope damilola
59 Ade-onojobi Adetutu A
60 Adejimi Oluyemisi Omolade
61 Oke Olumide Ibidapo
62 Nwabunwene Dumebi
63 Adegbite Doris Ebosereme
64 Ofana Rosaline Ujor
65 Bamidele Damilola Bimbola
66 Daramola Funmilayo Abosede
67 Sojobi Folasade Olajumoke
68 Sobulo Olaiya Ayodeji
69 Akinlade Dunmola Grace
70 Gbadebo-Aminu Faith Uyenikoshe
71 Oyalowo Adelola Morufat
72 Salu Oluseun Pius
73 Adefila Adenike Mutiat
74 Adekanmi Nofisat
75 Kehinde Bukola Hannah
76 Akinbile Olaide Olajumoke
77 Ajayi Mosunmola Ruth
78 Okewale Yetunde Victoria
79 Lasaki Risikat Abolade
80 Nwatune-Lambo Esther Omolara
81 Salihu Khadijat
82 Oke S. Olaolu
83 Akinmade Lydia Abimbola
84 Monye Edith
85 Nwafor Joy
86 Ogunseye Omolola Adesodun
87 Peru O. Julie
88 Ibekwe Nkowkag
89 Osaje Mirabel Ekele
90 Obidiegwu Jacinta
91 Onifade funmilayo
92 Ohen Grace Onyebushi
93 Tolu Oloko
94 Mobolaji Olajide
95 Ameye Modupe Funmilyo
96 Arilewola Omotola O
97 Akinyemi Josephine Omobola
98 Ubani P.E
99 Yusuf Rashidat Adebola
100 Ogunsola funke O
101 Mekwuye Friday
102 Asmau Saka Apalado
103 Aina Gbenuola Opeyemi
104 Ede Samson Nnamdi
105 Grace Abba
106 Chika Cecilia Ifeanyi
APPOINTMENT POST: MEDICAL LABORATORY TECHNICIAN
1 Mikail Rizquot Adebola
2 Oladele Mariam Olabisi
3 Odekunle Victoria Tosin
APPOINTMENT POST: ENVIRONMENTAL HEALTH OFFICER
1 Oni Adejumoke Oluwatoyin Easthen
2 Kadiri Olabisi Rashidat
APPOINTMENT POST: HIGHER NUTRITION OFFICER
1 Apata Christianah Bosede
2 Okunlola Oladimeji Busayo
APPOINTMENT POST: LEGAL OFFICER
1 Arinola Adebimpe Olasumbo
APPOINTMENT POST: PHARMACIST
1 Dada Sheriff Olajide
2 Owolabi Olutoke Damola
APPOINTMENT POST: PHARMACY TECHNICIAN
1 Oshode Oluwakemi Omoyemi
2 Ajayi Oluwafemi Adebowale
3 Babatunde Sabainah Arike
APPOINTMENT POST: RESEARCH OFFICER/ASSISTANT
1 Adeniji Adepeju Oluwakemi
2 Nweke Sunday O.
NOTE: All successful candidates whose names appeared above are requested to bring along the following to the establishment unit of administration department of the centre:
Applicants are invited from suitably qualified and experienced candidates for appointment into the following vacant positions in the Federal Medical Centre, Abeokuta, Ogun State.
(Chemical Pathology & Microbiology)
FOR POSTS 1-12
Candidates must possess MBBS or MB Ch B from recognized University as well as Fellowship of the Nigerian Post-Graduate Medical College or its equivalent, registrable with the Medical and Dental Council of Nigeria (MDCN). Previous working experience in their field of specialties will be an advantage.
FOR POSTS 13-16
Candidates must possess MBBS or MB Ch B or equivalent overseas qualifications registrable with the Medical and Dental Council of Nigeria (MDCN) as well as Primary Fellowship of either the National Postgraduate Medical College of Nigeria or West African College of Surgeons in the relevant field/specialty. Possession of Primary Fellowship in both Colleges will be an advantage.
FOR POST 17
Candidates must possess MBBS or MB Ch B or equivalent overseas qualifications registrable with the Medical and Dental Council of Nigeria (MDCN) and must have successfully completed the NYSC Programme.
FOR POST 18
Candidates must possess B.D.S or equivalent overseas qualifications registrable with the Medical and Dental Council of Nigeria (MDCN) and must have successfully completed the NYSC Programme.
FOR POST 19
Candidates must possess Bachelor of Pharmacy Degree (B.Pharm) registrable with the Pharmacist Registration Board of Nigeria (PRBN) and must have successfully completed the NYSC Programme.
FOR POST 20
Candidates must possess Bachelor’s Degree in Radiography (B.Rad) registrable with the Radiographers Registration Board of Nigeria (RRBN) and must have successfully completed the NYSC Programme.
FOR POST 21
Candidates must possess Bachelor’s Degree in Medical Laboratory Science (BMLS) registrable with the Medical Laboratory Science Council of Nigeria and must have successfully completed the NYSC Programme.
FOR POST 22
Candidates must possess LL.B and B.L qualifications and must have completed the NYSC Programme.
FOR POST 23
Candidates must possess a Master of Science (M.Sc) Degree in Architecture from recognized University and must have successfully completed the NYSC Programme. Must be professionally registered.
FOR POST 24
Candidates must possess a minimum of Higher National Diploma (HND) in Health Information Management registrable with Health Records Board of Nigeria (HRBN). Candidates must have successfully completed NYSC Programme.
FOR POST 25
Candidates must possess a minimum of Higher National Diploma (HND) in Dental Hygiene from recognized Institutions and must have completed the NYSC Programme.
FOR POST 26
Candidates must possess Bachelor’s degree in Dental Technology from recognized University and must have completed the NYSC Programme.
FOR POST 27
Candidates must possess a minimum of Higher National Diploma (HND) in Dietetics from recognized Institutions and must have completed the NYSC Programme.
FOR POST 28
Candidates must possess a minimum of a Degree or Higher National Diploma (HND) in Home Economics or Food Science from recognized Institutions and must have completed the NYSC Programme.
FOR POST 29
Candidates must possess a minimum of a Degree in Sciences or Social Sciences with NYSC Certificate. Previous experience in research activities will be an advantage.
FOR POST 30
Candidates must possess a minimum of Higher National Diploma (HND) in Environmental Health Sciences from recognized Institutions with an evidence of completion of NYSC Programme.
FOR POST 31
Additional qualifications in Nursing Sub-specialties such as Anaesthesia,
Peri-Operative, Renal, Ophthalmology, ENT, Intensive Care, Orthopaedic, Accident & Emergency, Paediatric Nursing will be an advantage.
FOR POST 32
Candidates must possess the Medical Laboratory Technician Certificate from recognized Institutions with evidence of registration with the Medical Laboratory Science Council of Nigeria.
FOR POST 33
Candidates must possess the Pharmacy Technician Certificate from recognized Institutions with evidence of registration with the Pharmacist Council of Nigeria.
FOR POST 34
Candidates must possess a Degree in Physiology or Higher National Diploma in Electrical/Electronic Engineering from recognized Institutions. In addition, candidates must have been certified as EEG Technician. Previous experience in a Teaching/Specialist hospital will be an advantage.
FOR POST 35
Candidates must possess Ordinary National Diploma (OND) in Health Information Management from recognized Institutions with evidence of registration with Health Records Board of Nigeria. Previous experience in Health Information Management in a Teaching/Specialist Hospital will be an advantage.
FOR POST 36
Candidates must possess a Bio-Medical Technician Certificate from recognized Institutions. Previous experience in Teaching/Specialist Hospital will be an advantage.
FOR POST 37
Candidates must possess Junior Secondary Certificate (JSS) or West African School Certificate/(WASC/NECO) with passes in four subjects.
FOR POST 38
Candidates must possess a minimum of First School Leaving Certificate (FSLC).
Conditions of Service
These are similar to those obtainable in the Federal Public Service.
Method of Application
Application forms are obtainable from the Office of the Medical Director, Federal Medical Centre, Abeokuta.
Applicants are to submit reference letters along with the completed application form to the Office of the Medical Director before the closing date. Referees’ reports brought on the date of the interview will be discountenanced.
Completed application forms, three referees’ reports, photocopies of relevant Certificates, Credentials and Curriculum Vitae (CV) should be addressed to:
The Medical Director
Federal Medical Centre,
Bisi Onabanjo Way, Idi-Aba,
P.M.B. 3031 (Sapon Post Office),
Six weeks from the date of publication.
N.B: Qualified candidates from the following states are especially encouraged to apply:
1. Taraba (2) Plateau (3) Cross River (4) Rivers (5) Enugu (6) Kastina (7) Sokoto (8) Kaduna (9) Yobe (10) Adamawa (11) Kano (12) FCT (13) Niger (14) Ebonyi (15) Bayelsa (16) Borno (17) Bauchi (18) Gombe (19) Jigawa (20) Kebbi (21) Nasarawa
O. A. Oyeku
Director of Administration
For: Medical Director
Dr. Rufus Akinyemi, Consultant Neurologist, FMC Abeokuta reports on a2010 IBRO Research Fellowship at the Institute for Ageing and Health, Newcastle University, United Kingdom
Stroke is a leading non-communicable disease all over the world, and current reports suggest that it is assuming epidemic proportions in middle and low- income countries. About 30% of stroke survivors ultimately develop vascular dementia even though the exact mechanisms are yet poorly understood. Moreover, much of what is known about the epidemiology, natural history and neurobiology of post-stroke cognitive dysfunction have had little contribution from sub-Saharan Africa.
With this background and my training in clinical neurology as well as being a witness of the evolving epidemiology of stroke and its short- and long term consequences in sub-Saharan Africa, I took up the prestigious IBRO Research Fellowship under the tutelage of Prof Raj Kalaria,Deputy Director of the MRC Newcastle Centre for Brain Ageing and Vitality at the Institute for Ageing and Health, Newcastle University, Newcastle upon Tyne, United Kingdom.
My work, in the course of the fellowship, involved a stinct in the Acute Stroke Unit of the Royal Victoria Infirmary (RVI), Newcastle upon Tyne, UK (Figure 1) as well as laboratory research centred on investigating the cellular and molecular mechanisms of cerebral injury and cognitive impairment after stroke (Figure 2).
Under the guidance of Prof Gary Ford, Director of the UK Stroke Research Network and a leading stroke physician based in the Stroke Centre of the RVI, the stinct in the Acute Stroke Unit exposed me to the state-of-the-art and cutting edge stroke medicine as practised in the centre. The timely triaging, rapid assessment, neuroimaging and thrombolytic intervention (when necessary) of cases of acute stroke were exciting, and the multidisciplinary approach to care including regular MDT meetings, post –discharge care, networking with community- based care providers and excellent patient follow ups provided an excellent model worthy of adaptation to a developing country setting. I also took time off, as much as time permitted, to attend the weekly educational programmes of the Department of Neurology of the RVI.
For the laboratory-based programme, we obtained human brain tissue from the Newcastle Brain Tissue Resource (NBTR) brain bank, including brain tissue that have accrued from the MRC (UK)- funded research programme on Cognitive Functions After Stroke (COGFAST) based in the Institute for Ageing and Health of the Newcastle University. We used markers of neurodegenerative pathology (amyloid, soluble amyloid oligomers and tau) and synaptic density (synaptophysin, drebrin and vesicular glutamate transporter), and the techniques of immunocytochemistry, in-vitro imaging and computer-based analysis with the Image Pro Plus software to investigate brain tissue sections obtained from the hippocampus and entorhinal cortex of the post-stroke cohort in comparison with normal controls, vascular dementia (VaD), Alzheimer’s disease (AD) and mixed AD/VaD.
The results showed increased accumulation of amyloid but relatively similar level of tau in post-stroke brains compared to normal controls, and much less than the amount of amyloid and tau quantified from the AD and mixed AD/ VaD brain tissue. In addition, we surprisingly found a higher level of amyloid (but relatively similar levels of tau) in non-demented than in demented post-stroke brains. We, however, found a significantly higher amount of drebrin, a post-synaptic marker, in the non-demented than in the demented post-stroke brains. This correlated with an earlier finding from the group of an higher volume of hippocampal CA1 sub-regional neurons in the non-demented compared to the demented post-stroke brains. Vascular pathologies were however similar between the non-demented and demented post-stroke groups.
These results suggest that hippocampal neurodegenerative and vascular pathologies interact with synaptic densities, neuronal volumes (and possibly other yet to be identified variables) to determine the cognitive trajectory after stroke, and that higher hippocampal synaptic density and neuronal volumes (possibly signatures of higher cognitive reserve) may protect against or delay the onset of dementia after stroke.
During the research fellowship, I also spearheaded the setting up of a parallel Nigerian longitudinal study to investigate the profile, determinants and outcome of cognitive dysfunction in Nigerian stroke survivors in collaboration with the established Newcastle COGFAST Project. The pilot study revealed cognitive dysfunction in 28% of 42 stroke survivors while the main study is currently in progress.
In addition, the fellowship period afforded me the opportunity of effective networking and contribution to the growth of African Neuroscience. The IBRO Alumni – Nigeria group was inaugurated to network and coordinate young Nigerian neuroscientists who have participated in IBRO programmes. I also served as editor, and contributed two review articles to an IBRO-sponsored special Neuroscience Edition of a growing African journal – Archives of Ibadan Medicine.
In all, the fellowship period was a great leap in my development and progress as a Neurophysician – scientist, and I look forward to making significant contributions to Neuroscience research, education and research capacity building in Africa and beyond in the years ahead.
The fellowship programme has enhanced the international image of the Federal Medical Centre Abeokuta and further strengthened the growing relationship between the centre and experts based in the Newcastle University, UK. An immediate outcome of this was a visit to the FMC Abeokuta by my UK host and mentor, Prof Rajesh Kalaria in December 2011. Some of the researches arising from the programme have been presented in international scientific conferences in the UK, France and Ethiopia while a number of publications are in preparation. The research exposure of this programme has also inspired me to spearhead the promotion of research culture in our centre through the recent inauguration of the FMC Abeokuta Research Forum. My colleagues and trainee postgraduate doctors in the Department of Internal Medicine have been positively influenced in the pursuit of clinical excellence and research mindedness.
Dr. Rufus Akinyemi
Division of Neurology, Department of Medicine
Federal Medical Centre, Abeokuta, NIGERIA.
email@example.com, mobile no: +234 803 3704 384